Tuesday, September 11, 2012

Helios - Multi-Channel Potentiostat


A potentiostat is the electronic hardware required to control a three electrode cell and is used to run most electroanalytical experiments. In electroanalytical experiments, it is often used to read the signal from sensor chips with an analyte.
This equipment is fundamental to modern electrochemical studies using voltammetry for investigations of reaction mechanisms related to redox chemistry and other chemical phenomena.

Helios
Multi-Channel Potentiostat

Helios is the first truly affordable multi-channel electrochemical workstation that has 16 independent channels, all with independently addressable control. Its channel configuration is easy to use and efficient – capable of performing up to 16 different electrochemical experiments at the same time.
The Helios, as well as our electrochemical sensor chips, is a great representation of our novel sensor technology that is unlike the conventional electrochemical sensor chip and potentiostat combination. Using our universal technology platform, experiments such as electrolyte assays, genetic assays, and immunoassays are able to be performed using raw samples - no PCR required; yielding precise, quantitative results in under an hour.
By adapting the advanced USB connection, Helios is sleek and compact in design like no other of its kind; providing you with the utmost performance – through the use of just one cable.

Helios Applications – Electroanalysis

Electrochemical research is a broad research field and directly contributes to a wide variety of applications in the medical field. GeneFluidics’ Helios currently focuses and contributes in the fields of pathogen identification, antimicrobial susceptibility testing (AST), and cancer biomarker screening.
In all fields of diagnostics, accuracy, reliability, and speed are very essential factors. In answer to that, GeneFluidics develops highly sensitive and efficient detection platforms and point-of-care research systems to deliver prompt, precise results for research in medicine and other life sciences. GeneFluidics is working to develop and optimize products that will be more reliable and easy-to-use in hospital and clinical settings. Pursuant to that goal, we have been in close collaboration with physicians in urology, pediatric pathology, and oral oncology.
As a case in point, typical microbial analysis of bacterial infections relies on a culturing process requiring one to three days before results are available. This often forces clinicians to prescribe antibiotics before test results are available. Driven by this heedless prescription of antibiotics, emergence of drug-resistant pathogens has been a growing threat to global health.
With the GeneFluidics’ detection technology, rapid antimicrobial susceptibility testing (AST) is possible. We are capable of cutting the required days it takes to provide susceptibility data to a matter of just hours. This revolutionary platform could enable clinicians to treat patients based on accurate pathogen identification and resistance information without promoting the growth of drug-resistant pathogens.

Electrochemical Sensor Chip


                The electrochemical sensor chip is the backbone of our sensor technology. On each sensor chip, 16 independent assays can be performed for 16 different assays. With GeneFluidics’ novel electrochemical detection platform, it enables the achievement of ultra-high sensitivity without target amplification or purification, such as PCR, by combining the established technologies of hybridization and antigen/antibody interactions with well characterized electrochemical measurement techniques.

            Our sensor chip’s surface can even be modified to better fit your needs. The types of surface modifications we can provide include sensors with bare Au, a high or low density carboxylic, streptavidin, and even customized surfaces.


            Our detection mechanism is able to yield such great results because our sensor chip is a full representation of our patented sensor fabrication and electrochemical detection platform. Our sensor technology enables quantification of nucleic acids and proteins in even raw samples such as blood, urine, and saliva. The sensor surfaces are functionalized to bind specifically to the target molecule, so that when the sample is added, only the specific binding occurs at the functionalized sensor. So during the wash, all of the non-specific binding is washed away. Using this method, our electrochemical detection platform is able to yield precise and quantitative results in under an hour.